Spinach Peptide Treatment Gains EPA Approval for Citrus

EPA approval clears the way for a new treatment designed to help citrus trees fight greening disease.

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Citrus greening, or Huanglongbing, inflicts approximately $3 billion in agricultural losses each year. Finding novel solutions for the disease has become a high priority for AgriLife Research, which has developed new screening methods and potential treatments in response to the disease’s continued spread. (Sam Craft/Texas A&M AgriLife)

Photo by Sam Craft via Texas A&M AgriLife

WESLACO, Texas (RFD News) — A new citrus greening treatment developed from spinach-derived antimicrobial peptides has received unconditional registration from the U.S. Environmental Protection Agency, clearing the way for commercial use. The technology emerged from more than 15 years of research led by Texas A&M AgriLife and collaborating institutions.

The treatment uses naturally occurring spinach defensins delivered through a non-transmissible strain of citrus tristeza virus already found in Florida citrus trees. The virus prompts treated trees to continuously produce the defensin peptide without altering the tree’s genome.

Researchers say the approach functions much like an immunization, helping trees fight the bacteria associated with Huanglongbing, or citrus greening. The disease has severely reduced citrus production and tree productivity in affected regions.

Maryland-based Silvec Biologics holds registration for the commercial product and expects Florida growers to begin gaining access through the Citrus Research and Field Trial program late this year.

Researchers are also studying spinach defensins against other crop diseases, including zebra chip in potatoes, potentially expanding the technology beyond citrus.

Farm-Level Takeaway: EPA approval provides citrus growers with a new disease-management option to keep infected trees productive longer.
Tony St. James, RFD News Markets Specialist

Tony St. James joined the RFD-TV talent team in August 2024, bringing a wealth of experience and a fresh perspective to RFD-TV and Rural Radio Channel 147 Sirius XM. In addition to his role as Market Specialist (collaborating with Scott “The Cow Guy” Shellady to provide radio and TV audiences with the latest updates on ag commodity markets), he hosts “Rural America Live” and serves as talent for trade shows.

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