CRISPR Technology Opens New Chapter in Agricultural Pest Control

Bryan Witherbee, the CEO of Agragene, says the technology builds on the sterile insect technique, which successfully helped eliminate pink bollworm and New World Screwworm in the past.

LUBBOCK, Texas (RFD-TV) — Agriculture may be entering a new era of insect management as gene-editing technology moves beyond the laboratory and toward commercial use.

Agragene is developing a precision-guided sterile insect technique that could give producers another tool to reduce damaging insect populations while lowering dependence on traditional insecticides.

Bryan Witherbee is the CEO of Agragene and says the technology builds on the sterile insect technique, which successfully helped eliminate pink bollworm from U.S. cotton fields and push New World screwworm out of the country decades ago.

Instead of sterilizing both male and female insects with radiation, the new system uses CRISPR gene-editing to produce only sterile males. Those insects compete with wild males for mating, making population control more efficient and potentially less expensive.

The approach could eventually be adapted to multiple invasive pests affecting crops and livestock while reducing pesticide applications and preserving beneficial insects. Witherbee says precision, scalability, and lower production costs could make the technology practical for agriculture.

Researchers continue evaluating the system, including its potential role in future USDA pest management programs.

Farm-Level Takeaway: Precision sterile insect technology could become another important tool alongside pesticides, biological controls, and genetics to manage costly invasive pests.
Tony St. James, RFD-TV Markets Specialist

Tony St. James joined the RFD-TV talent team in August 2024, bringing a wealth of experience and a fresh perspective to RFD-TV and Rural Radio Channel 147 Sirius XM. In addition to his role as Market Specialist (collaborating with Scott “The Cow Guy” Shellady to provide radio and TV audiences with the latest updates on ag commodity markets), he hosts “Rural America Live” and serves as talent for trade shows.

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